Human islets contain four distinct subtypes of β cells

Human pancreatic islets of Langerhans contain five distinct endocrine cell types, each producing a characteristic hormone. The dysfunction or loss of the insulin-producing β cells causes diabetes mellitus, a disease that harms millions. Until now, β cells were generally regarded as a single, homogen...

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Publicat a:Nat Commun
Autors principals: Dorrell, Craig, Schug, Jonathan, Canaday, Pamela S., Russ, Holger A., Tarlow, Branden D., Grompe, Maria T., Horton, Tamara, Hebrok, Matthias, Streeter, Philip R., Kaestner, Klaus H., Grompe, Markus
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942571/
https://ncbi.nlm.nih.gov/pubmed/27399229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11756
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