Modeling Interactions among Individual P2 Receptors to Explain Complex Response Patterns over a Wide Range of ATP Concentrations

Extracellular ATP acts on the P2X family of ligand-gated ion channels and several members of the P2Y family of G protein-coupled receptors to mediate intercellular communication among many cell types including bone-forming osteoblasts. It is known that multiple P2 receptors are expressed on osteobla...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Xing, Shu, Grol, Matthew W., Grutter, Peter H., Dixon, S. Jeffrey, Komarova, Svetlana V.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942464/
https://ncbi.nlm.nih.gov/pubmed/27468270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00294
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