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Bifurcation-based approach reveals synergism and optimal combinatorial perturbation

Cells accomplish the process of fate decisions and form terminal lineages through a series of binary choices in which cells switch stable states from one branch to another as the interacting strengths of regulatory factors continuously vary. Various combinatorial effects may occur because almost all...

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Vydáno v:J Biol Phys
Hlavní autoři: Liu, Yanwei, Li, Shanshan, Liu, Zengrong, Wang, Ruiqi
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942421/
https://ncbi.nlm.nih.gov/pubmed/27079194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-016-9414-7
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