Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Non-Surgical Bleeding

BACKGROUND: Non-surgical bleeding (NSB) is the most common adverse event in patients with continuous-flow left ventricular assist devices (LVADs) and is caused by arteriovenous malformations (AVMs). We hypothesized that deregulation of an angiogenic factor, Angiopoietin-2 (Ang-2), in LVAD patients l...

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Pubblicato in:Circulation
Autori principali: Tabit, Corey E., Chen, Phetcharat, Kim, Gene H., Fedson, Savitri E., Sayer, Gabriel, Coplan, Mitchell J., Jeevanandam, Valluvan, Uriel, Nir, Liao, James K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942355/
https://ncbi.nlm.nih.gov/pubmed/27354285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.019692
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