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Increased numbers of CD23(+)CD21(hi) Bin-like B cells in human reactive and rheumatoid arthritis lymph nodes

A unique population of CD23(+) CD21(high) B cells in inflamed nodes (Bin) has been shown to accumulate in lymph nodes (LNs) draining inflamed joints of TNF-transgenic (TNF-tg) mice. Bin cells contribute to arthritis flare in mice by distorting node architecture and hampering lymphatic flow, but thei...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Kuzin, Igor I., Kates, Stephen L., Ju, Yawen, Zhang, Longze, Rahimi, Homaira, Wojciechowski, Wojciech, Bernstein, Steven H., Burack, Richard, Schwarz, Edward M., Bottaro, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942352/
https://ncbi.nlm.nih.gov/pubmed/27105894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546266
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