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Genes with monoallelic expression contribute disproportionately to genetic diversity in humans
An unexpectedly large number of human autosomal genes are subject to monoallelic expression (MAE). Our analysis of 4,227 such genes reveals surprisingly high genetic variation across human populations. This increased diversity is unlikely to reflect relaxed purifying selection. Remarkably, MAE genes...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942303/ https://ncbi.nlm.nih.gov/pubmed/26808112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3493 |
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