Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation

Activation of inflammatory pathways represents a central mechanism in multiple disease states both acute and chronic. Triggered via either pathogen or tissue damage-associated molecular motifs, common biochemical pathways lead to conserved yet variable physiological and immunological alterations. Di...

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Udgivet i:J Vis Exp
Main Authors: Fullerton, James N., Segre, Elisabetta, De Maeyer, Roel P.H., Maini, Alexander A.N., Gilroy, Derek W.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2016
Fag:
Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942172/
https://ncbi.nlm.nih.gov/pubmed/27213711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53913
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