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Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration

Sustained liver fibrosis with continuation of extracellular matrix (ECM) protein build-up results in the loss of cellular competency of the liver, leading to cirrhosis with hepatocellular dysfunction. Among multiple hepatic insults, alcohol abuse can lead to significant health problems including liv...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Huang, Mianbo, Xu, Jin, Shin, Chong Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942144/
https://ncbi.nlm.nih.gov/pubmed/27214059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54002
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