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Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

The only formula of dacarbazine (Dac) in clinical use is intravenous infusion, presenting a poor therapeutic profile due to the low dispersity of the drug in aqueous solution. To overcome this, a nanostructured lipid carrier (NLC) consisting of glyceryl palmitostearate and isopropyl myristate was de...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Almoussalam, Musallam, Zhu, Huijun
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942000/
https://ncbi.nlm.nih.gov/pubmed/27168058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53760
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