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The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome

Copy number variations to chromosome 21 (HSA21) cause intellectual disability and Down Syndrome, but our understanding of the HSA21 genetic factors which contribute to fetal brain development remains incomplete. Here, we focussed on the neurodevelopmental functions for EURL (also known as C21ORF91,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Shan Shan, Qu, Zhengdong, Haas, Matilda, Ngo, Linh, Heo, You Jeong, Kang, Hyo Jung, Britto, Joanne Maria, Cullen, Hayley Daniella, Vanyai, Hannah Kate, Tan, Seong-Seng, Chan-Ling, Tailoi, Gunnersen, Jenny Margaret, Heng, Julian Ik-Tsen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941730/
https://ncbi.nlm.nih.gov/pubmed/27404227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29514
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