Cardiac myosin light chain is phosphorylated by Ca(2+)/calmodulin-dependent and -independent kinase activities

The well-known, muscle-specific smooth muscle myosin light chain kinase (MLCK) (smMLCK) and skeletal muscle MLCK (skMLCK) are dedicated protein kinases regulated by an autoregulatory segment C terminus of the catalytic core that blocks myosin regulatory light chain (RLC) binding and phosphorylation...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Chang, Audrey N., Mahajan, Pravin, Knapp, Stefan, Barton, Hannah, Sweeney, H. Lee, Kamm, Kristine E., Stull, James T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941474/
https://ncbi.nlm.nih.gov/pubmed/27325775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600633113
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