Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model

BACKGROUND: MYCN-amplification in high-grade Neuroblastoma (NB) tumors correlates with increased vascularization and therapy resistance. This study combines an anti-angiogenic approach with targeting NB metabolism for treatment. METHODS AND RESULTS: Metronomic cyclophosphamide (MCP) monotherapy sign...

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Publicat a:Oncotarget
Autors principals: Morscher, Raphael Johannes, Aminzadeh-Gohari, Sepideh, Hauser-Kronberger, Cornelia, Feichtinger, René Günther, Sperl, Wolfgang, Kofler, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941371/
https://ncbi.nlm.nih.gov/pubmed/26959744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7929
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