p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

p85α is a regulatory subunit of phosphatidylinositol 3-kinase (PI3K) that is a key lipid enzyme for generating phosphatidylinositol 3, 4, 5-trisphosphate, and subsequently activates signaling that ultimately regulates cell cycle progression, cell growth, cytoskeletal changes, and cell migration. In...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Xie, Qipeng, Guo, Xirui, Gu, Jiayan, Zhang, Liping, Jin, Honglei, Huang, Haishan, Li, Jingxia, Huang, Chuanshu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941340/
https://ncbi.nlm.nih.gov/pubmed/26918608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7674
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