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Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation

Podoplanin (PDPN) is a transmembrane glycoprotein that plays crucial roles in embryonic development, the immune response, and malignant progression. Here, we report that cells ectopically or endogenously expressing PDPN release extracellular vesicles (EVs) that contain PDPN mRNA and protein. PDPN in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Carrasco-Ramírez, Patricia, Greening, David W., Andrés, Germán, Gopal, Shashi K., Martín-Villar, Ester, Renart, Jaime, Simpson, Richard J., Quintanilla, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941298/
https://ncbi.nlm.nih.gov/pubmed/26893367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7445
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