Protective effect of α-lipoic acid against radiation-induced fibrosis in mice

Radiation-induced fibrosis (RIF) is one of the most common late complications of radiation therapy. We found that α-lipoic acid (α-LA) effectively prevents RIF. In RIF a mouse model, leg contracture assay was used to test the in vivo efficacy of α-LA. α-LA suppressed the expression of pro-fibrotic g...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ryu, Seung-Hee, Park, Eun-Young, Kwak, Sungmin, Heo, Seung-Ho, Ryu, Je-Won, Park, Jin-hong, Choi, Kyung-Chul, Lee, Sang-wook
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941260/
https://ncbi.nlm.nih.gov/pubmed/26799284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6952
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