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The Multiple Faces of RAGE - Opportunities for Therapeutic Intervention in Aging and Chronic Disease

INTRODUCTION: This review focuses on the multi-ligand receptor of the immunoglobulin superfamily, receptor for advanced glycation endproducts (RAGE). The accumulation of the multiple ligands of RAGE in cellular stress milieux links RAGE to the pathobiology of chronic disease and natural aging. AREAS...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Ramasamy, Ravichandran, Shekhtman, Alexander, Schmidt, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941230/
https://ncbi.nlm.nih.gov/pubmed/26558318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2016.1111873
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