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Supramolecular Glycosylation Accelerates Proteolytic Degradation of Peptide Nanofibrils

[Image: see text] Despite the recent consensus that the oligomers of amyloid peptides or aberrant proteins are cytotoxic species, there is still a need for an effective way to eliminate the oligomers. Based on the fact that normal proteins are more glycosylated than pathogenic proteins, we show that...

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Publicat a:J Am Chem Soc
Autors principals: Yuan, Dan, Shi, Junfeng, Du, Xuewen, Zhou, Ning, Xu, Bing
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941208/
https://ncbi.nlm.nih.gov/pubmed/26237170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05888
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