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Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination

Synaptic inhibition in the olfactory bulb (OB), the first relay station of olfactory information, is believed to be important for odour discrimination. We interfered with GABAergic inhibition of mitral and tufted cells (M/T cells), the principal neurons of the OB, by disrupting their potassium-chlor...

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Pubblicato in:Nat Commun
Autori principali: Gödde, Kathrin, Gschwend, Olivier, Puchkov, Dmytro, Pfeffer, Carsten K., Carleton, Alan, Jentsch, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941119/
https://ncbi.nlm.nih.gov/pubmed/27389623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12043
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