Induction of differentiation in psoriatic keratinocytes by propylthiouracil and fructose()

Psoriasis is characterized by uncontrolled proliferation and poor differentiation. Sirtuin1 (SIRT1) a class III deacetylase, crucial for differentiation in normal keratinocytes, is reduced in psoriasis. Down regulated SIRT1 levels may contribute to poor differentiation in psoriasis. In addition, the...

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Vydáno v:BBA Clin
Hlavní autoři: Arul, Santhosh, Dayalan, Haripriya, Jegadeesan, Muhilan, Damodharan, Prabhavathy
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941040/
https://ncbi.nlm.nih.gov/pubmed/27453822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2016.06.002
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