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Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in mice
BACKGROUND: Peripheral neuropathy is a common and dose-limiting side effect of many cancer chemotherapies. The taxane agents, including paclitaxel (Taxol(®)), are effective chemotherapeutic drugs but cause degeneration of predominantly large myelinated afferent sensory fibers of the peripheral nervo...
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| Pubblicato in: | BMC Neurosci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940970/ https://ncbi.nlm.nih.gov/pubmed/27401104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0285-4 |
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