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Effects of new‐generation inhibitors of the calcium‐activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract

BACKGROUND AND PURPOSE: High‐throughput screening of compound libraries using genetically encoded fluorescent biosensors has identified several second‐generation. low MW inhibitors of the calcium‐activated chloride channel anoctamin 1 (CaCC/Ano1). Here we have (i) examined the effects of these Ano1...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Hwang, Sung Jin, Basma, Naseer, Sanders, Kenton M, Ward, Sean M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940814/
https://ncbi.nlm.nih.gov/pubmed/26774021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13431
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