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Cholangiocarcinoma-derived exosomes inhibit the antitumor activity of cytokine-induced killer cells by down-regulating the secretion of tumor necrosis factor-α and perforin

Objective: The aim of our study is to observe the impact of cholangiocarcinoma-derived exosomes on the antitumor activities of cytokine-induced killer (CIK) cells and then demonstrate the appropriate mechanism. Methods: Tumor-derived exosomes (TEXs), which are derived from RBE cells (human cholangio...

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Dades bibliogràfiques
Publicat a:J Zhejiang Univ Sci B
Autors principals: Chen, Jiong-huang, Xiang, Jian-yang, Ding, Guo-ping, Cao, Li-ping
Format: Artigo
Idioma:Inglês
Publicat: Zhejiang University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940629/
https://ncbi.nlm.nih.gov/pubmed/27381730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1500266
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