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Long-Term Tolerability, Safety, and Efficacy of Recombinant Human Hyaluronidase-Facilitated Subcutaneous Infusion of Human Immunoglobulin for Primary Immunodeficiency

PURPOSE: Treatment of primary immunodeficiency diseases (PIDD) with subcutaneous (SC) infusions of IgG preceded by injection of recombinant human hyaluronidase (rHuPH20) (IGHy) to increase SC tissue permeability was evaluated in two consecutive, prospective, non-controlled, multi-center studies. MET...

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Detalhes bibliográficos
Publicado no:J Clin Immunol
Main Authors: Wasserman, Richard L., Melamed, Isaac, Stein, Mark R., Engl, Werner, Sharkhawy, Marlies, Leibl, Heinz, Puck, Jennifer, Rubinstein, Arye, Kobrynski, Lisa, Gupta, Sudhir, Grant, Andrew J., Ratnayake, Anoshie, Richmond, Wendell G., Church, Joseph, Yel, Leman, Gelmont, David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940441/
https://ncbi.nlm.nih.gov/pubmed/27220317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-016-0298-x
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