Long-Term Tolerability, Safety, and Efficacy of Recombinant Human Hyaluronidase-Facilitated Subcutaneous Infusion of Human Immunoglobulin for Primary Immunodeficiency

PURPOSE: Treatment of primary immunodeficiency diseases (PIDD) with subcutaneous (SC) infusions of IgG preceded by injection of recombinant human hyaluronidase (rHuPH20) (IGHy) to increase SC tissue permeability was evaluated in two consecutive, prospective, non-controlled, multi-center studies. MET...

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Publicado en:J Clin Immunol
Autores principales: Wasserman, Richard L., Melamed, Isaac, Stein, Mark R., Engl, Werner, Sharkhawy, Marlies, Leibl, Heinz, Puck, Jennifer, Rubinstein, Arye, Kobrynski, Lisa, Gupta, Sudhir, Grant, Andrew J., Ratnayake, Anoshie, Richmond, Wendell G., Church, Joseph, Yel, Leman, Gelmont, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940441/
https://ncbi.nlm.nih.gov/pubmed/27220317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-016-0298-x
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