Involvement of Cyclic Guanosine Monophosphate-Dependent Protein Kinase I in Renal Antifibrotic Effects of Serelaxin

Introduction: Kidney fibrosis has shown to be ameliorated through the involvement of cyclic guanosine monophosphate (cGMP) and its dependent protein kinase I (cGKI). Serelaxin, the recombinant form of human relaxin-II, increases cGMP levels and has shown beneficial effects on kidney function in acut...

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Foilsithe in:Front Pharmacol
Main Authors: Wetzl, Veronika, Schinner, Elisabeth, Kees, Frieder, Hofmann, Franz, Faerber, Lothar, Schlossmann, Jens
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016
Ábhair:
Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940422/
https://ncbi.nlm.nih.gov/pubmed/27462268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00195
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