Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

Essential biological systems employ self-correcting mechanisms to maintain cellular homeostasis. Mammalian cell function is dynamically regulated by the interaction of cell surface galectins with branched N-glycans. Here we report that N-glycan branching deficiency triggers the Golgi to generate bio...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mkhikian, Haik, Mortales, Christie-Lynn, Zhou, Raymond W, Khachikyan, Khachik, Wu, Gang, Haslam, Stuart M, Kavarian, Patil, Dell, Anne, Demetriou, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940165/
https://ncbi.nlm.nih.gov/pubmed/27269286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14814
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