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PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells

Mutations in PROP1 are the most common cause of hypopituitarism in humans; therefore, unraveling its mechanism of action is highly relevant from a therapeutic perspective. Our current understanding of the role of PROP1 in the pituitary gland is limited to the repression and activation of the pituita...

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Bibliographic Details
Published in:eLife
Main Authors: Pérez Millán, María Inés, Brinkmeier, Michelle L, Mortensen, Amanda H, Camper, Sally A
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940164/
https://ncbi.nlm.nih.gov/pubmed/27351100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14470
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