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Rates and Mechanisms of Bacterial Mutagenesis from Maximum-Depth Sequencing
In 1943, Luria and Delbrück used a phage resistance assay to establish spontaneous mutation as a driving force of microbial diversity(1). Mutation rates are still studied using such assays, but these can only examine the small minority of mutations conferring survival in a particular condition. Newe...
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| Publicado en: | Nature |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940094/ https://ncbi.nlm.nih.gov/pubmed/27338792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18313 |
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