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Improving the Sensitivity, Resolution, and Peak Capacity of Gradient Elution in Capillary Liquid Chromatography with Large-Volume Injections by Using Temperature-Assisted On-Column Solute Focusing

Capillary HPLC (cLC) with gradient elution is the separation method of choice for the fields of proteomics and metabolomics. This is due to the complementary nature of cLC flow rates and electrospray or nanospray ionization mass spectrometry (ESI-MS). The small column diameters result in good mass s...

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Vydáno v:Anal Chem
Hlavní autoři: Wilson, Rachael E., Groskreutz, Stephen R., Weber, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940048/
https://ncbi.nlm.nih.gov/pubmed/27033165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b04793
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