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Prolonged benefit from ipilimumab correlates with improved outcomes from subsequent pembrolizumab

Patients with metastatic melanoma who progress on ipilimumab can clearly derive benefit to subsequent anti-PD-1 (programmed death-1). However, patients experience heterogeneous outcomes with ipilimumab, including rapid or delayed progression, and it is unclear whether patterns of ipilimumab progress...

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Publicat a:Cancer Immunol Res
Autors principals: Shreders, Amanda, Joseph, Richard, Peng, Chengwei, Ye, Fei, Zhao, Shilin, Puzanov, Igor, Sosman, Jeffrey A., Johnson, Douglas B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940026/
https://ncbi.nlm.nih.gov/pubmed/27197063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0281
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