Evaluation of a Novel HA/ZrO(2)-Based Porous Bioceramic Artificial Vertebral Body Combined with a rhBMP-2/Chitosan Slow-Release Hydrogel

A new HA/ZrO(2)-based porous bioceramic artificial vertebral body (AVB), carried a recombinant human bone morphogenetic protein-2 (rhBMP-2)/chitosan slow-release hydrogel was prepared to repair vertebral bone defect in beagles. An ionic cross-linking was used to prepare the chitosan hydrogel (CS gel...

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Pubblicato in:PLoS One
Autori principali: Shi, Yihui, Quan, Renfu, Xie, Shangju, Li, Qiang, Cao, Guoping, Zhuang, Wei, Zhang, Liang, Shao, Rongxue, Yang, Disheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939960/
https://ncbi.nlm.nih.gov/pubmed/27400197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157698
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