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Toward Computationally Designed Self-Reporting Biosensors Using Leave-One-Out Green Fluorescent Protein

Leave-one-out green fluorescent protein (LOOn-GFP) is a circularly permuted and truncated GFP lacking the nth β-strand element. LOO7-GFP derived from the wild-type sequence (LOO7-WT) folds and reconstitutes fluorescence upon addition of β-strand 7 (S7) as an exogenous peptide. Computational protein...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Huang, Yao-ming, Banerjee, Shounak, Crone, Donna E., Schenkelberg, Christian D., Pitman, Derek J., Buck, Patrick M., Bystroff, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939794/
https://ncbi.nlm.nih.gov/pubmed/26397806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00786
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