Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis

Human endometrium undergoes cyclic regeneration involving stem/progenitor cells, but the role of resident endometrial mesenchymal stem cells (eMSC) as progenitors of endometrial stromal fibroblasts (eSF) has not been definitively demonstrated. In endometriosis, eSF display progesterone (P(4)) resist...

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Veröffentlicht in:Biol Reprod
Hauptverfasser: Barragan, Fatima, Irwin, Juan C., Balayan, Shaina, Erikson, David W., Chen, Joseph C., Houshdaran, Sahar, Piltonen, Terhi T., Spitzer, Trimble L.B., George, Ashley, Rabban, Joseph T., Nezhat, Camran, Giudice, Linda C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939744/
https://ncbi.nlm.nih.gov/pubmed/27075616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.136010
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