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Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin.

We have treated rat brain synaptoneurosomes with the crosslinking agent N,N'-1,4-phenylenedimaleimide under conditions that cause extensive crosslinking of tubulin, F-actin, and the alpha and beta subunits of three major types of heterotrimeric GTP-binding regulatory proteins (G(o), Gs, Gi) present...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Coulter, S, Rodbell, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.5842
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