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Water and Ion Permeability of a Claudin Model: A Computational Study

At present, the three-dimensional structure of the multimeric paracellular claudin pore is unknown. Using extant biophysical data concerning the size of the pore and permeation of water and cations through it, two three-dimensional models of the pore are constructed in silico. Molecular Dynamics (MD...

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Detalles Bibliográficos
Publicado en:Proteins
Main Authors: Laghaei, Rozita, Yu, Alan S.L., Coalson, Rob D.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939073/
https://ncbi.nlm.nih.gov/pubmed/26650625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24969
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