The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity

BACKGROUND: The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions. While emerging sequencing platforms are capable of producing several kilobases-long reads, the fragment sizes gen...

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Detalles Bibliográficos
Publicado en:BMC Genomics
Autores principales: Dapprich, Johannes, Ferriola, Deborah, Mackiewicz, Kate, Clark, Peter M., Rappaport, Eric, D’Arcy, Monica, Sasson, Ariella, Gai, Xiaowu, Schug, Jonathan, Kaestner, Klaus H., Monos, Dimitri
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938946/
https://ncbi.nlm.nih.gov/pubmed/27393338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2836-6
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