The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity

BACKGROUND: The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions. While emerging sequencing platforms are capable of producing several kilobases-long reads, the fragment sizes gen...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Dapprich, Johannes, Ferriola, Deborah, Mackiewicz, Kate, Clark, Peter M., Rappaport, Eric, D’Arcy, Monica, Sasson, Ariella, Gai, Xiaowu, Schug, Jonathan, Kaestner, Klaus H., Monos, Dimitri
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938946/
https://ncbi.nlm.nih.gov/pubmed/27393338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2836-6
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