A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice

Human papilliomavirus (HPV) oncogene E7, essential for the transformation and maintenance of the malignancy of cervical cancer cells, represents an ideal tumor-specific antigen for vaccine development. However, due to the poor immunogenicity of E7 protein, an effective therapeutic E7 vaccine is stil...

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Vydáno v:Oncoimmunology
Hlavní autoři: Liu, Zhida, Zhou, Hang, Wang, Wenjun, Fu, Yang-Xin, Zhu, Mingzhao
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938372/
https://ncbi.nlm.nih.gov/pubmed/27471615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1147641
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