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Nucleoside Triphosphate Phosphohydrolase I (NPH I) Functions as a 5′ to 3′ Translocase in Transcription Termination of Vaccinia Early Genes

Vaccinia virus early genes are transcribed immediately upon infection. Nucleoside triphosphate phosphohydrolase I (NPH I) is an essential component of the early gene transcription complex. NPH I hydrolyzes ATP to release transcripts during transcription termination. The ATPase activity of NPH I requ...

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Pubblicato in:J Biol Chem
Autori principali: Hindman, Ryan, Gollnick, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938199/
https://ncbi.nlm.nih.gov/pubmed/27189950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730135
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