The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β(2)-Adrenergic Receptor

Arrestin domain-containing protein 3 (ARRDC3) is a member of the mammalian α-arrestin family, which is predicted to share similar tertiary structure with visual-/β-arrestins and also contains C-terminal PPXY motifs that mediate interaction with E3 ubiquitin ligases. Recently, ARRDC3 has been propose...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Tian, Xufan, Irannejad, Roshanak, Bowman, Shanna L., Du, Yang, Puthenveedu, Manojkumar A., von Zastrow, Mark, Benovic, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938174/
https://ncbi.nlm.nih.gov/pubmed/27226565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716589
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