The interaction of PRC2 with RNA or chromatin is mutually antagonistic

Polycomb repressive complex 2 (PRC2) modifies chromatin to maintain genes in a repressed state during development. PRC2 is primarily associated with CpG islands at repressed genes and also possesses RNA binding activity. However, the RNAs that bind PRC2 in cells, the subunits that mediate these inte...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Beltran, Manuel, Yates, Christopher M., Skalska, Lenka, Dawson, Marcus, Reis, Filipa P., Viiri, Keijo, Fisher, Cynthia L., Sibley, Christopher R., Foster, Benjamin M., Bartke, Till, Ule, Jernej, Jenner, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937559/
https://ncbi.nlm.nih.gov/pubmed/27197219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.197632.115
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