Glucose and Palmitate Differentially Regulate PFKFB3/iPFK2 and Inflammatory Responses in Mouse Intestinal Epithelial Cells

The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Botchlett, Rachel, Li, Honggui, Guo, Xin, Qi, Ting, Zhao, JiaJia, Zheng, Juan, Woo, Shih-Lung, Pei, Ya, Liu, Mengyang, Hu, Xiang, Chen, Guang, Guo, Ting, Yang, Sijun, Li, Qifu, Xiao, Xiaoqiu, Huo, Yuqing, Wu, Chaodong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937440/
https://ncbi.nlm.nih.gov/pubmed/27387960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28963
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