Zero-valent Fe confined mesoporous silica nanocarriers (Fe(0) @ MCM-41) for targeting experimental orthotopic glioma in rats

Mesoporous silica nanoparticles (MSNs) impregnated with zero-valent Fe (Fe(0) @ MCM-41) represent an attractive nanocarrier system for drug delivery into tumor cells. The major goal of this work was to assess whether MSNs can penetrate the blood-brain barrier in a glioblastoma rat model. Synthesized...

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Publicat a:Sci Rep
Autors principals: Shevtsov, M. A., Parr, M. A., Ryzhov, V. A., Zemtsova, E. G., Arbenin, A. Yu, Ponomareva, A. N., Smirnov, V. M., Multhoff, G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937429/
https://ncbi.nlm.nih.gov/pubmed/27386761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29247
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