TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus

Influenza A and B viruses show clear differences in their host specificity and pandemic potential. Recent studies have revealed that the host protease TMPRSS2 plays an essential role for proteolytic activation of H1, H3, and H7 subtype strains of influenza A virus (IAV) in vivo. IAV possessing a mon...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Sakai, Kouji, Ami, Yasushi, Nakajima, Noriko, Nakajima, Katsuhiro, Kitazawa, Minori, Anraku, Masaki, Takayama, Ikuyo, Sangsriratanakul, Natthanan, Komura, Miyuki, Sato, Yuko, Asanuma, Hideki, Takashita, Emi, Komase, Katsuhiro, Takehara, Kazuaki, Tashiro, Masato, Hasegawa, Hideki, Odagiri, Takato, Takeda, Makoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937385/
https://ncbi.nlm.nih.gov/pubmed/27389476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29430
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