TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus

Influenza A and B viruses show clear differences in their host specificity and pandemic potential. Recent studies have revealed that the host protease TMPRSS2 plays an essential role for proteolytic activation of H1, H3, and H7 subtype strains of influenza A virus (IAV) in vivo. IAV possessing a mon...

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Publicado no:Sci Rep
Main Authors: Sakai, Kouji, Ami, Yasushi, Nakajima, Noriko, Nakajima, Katsuhiro, Kitazawa, Minori, Anraku, Masaki, Takayama, Ikuyo, Sangsriratanakul, Natthanan, Komura, Miyuki, Sato, Yuko, Asanuma, Hideki, Takashita, Emi, Komase, Katsuhiro, Takehara, Kazuaki, Tashiro, Masato, Hasegawa, Hideki, Odagiri, Takato, Takeda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937385/
https://ncbi.nlm.nih.gov/pubmed/27389476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29430
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