TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus

Influenza A and B viruses show clear differences in their host specificity and pandemic potential. Recent studies have revealed that the host protease TMPRSS2 plays an essential role for proteolytic activation of H1, H3, and H7 subtype strains of influenza A virus (IAV) in vivo. IAV possessing a mon...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Sakai, Kouji, Ami, Yasushi, Nakajima, Noriko, Nakajima, Katsuhiro, Kitazawa, Minori, Anraku, Masaki, Takayama, Ikuyo, Sangsriratanakul, Natthanan, Komura, Miyuki, Sato, Yuko, Asanuma, Hideki, Takashita, Emi, Komase, Katsuhiro, Takehara, Kazuaki, Tashiro, Masato, Hasegawa, Hideki, Odagiri, Takato, Takeda, Makoto
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937385/
https://ncbi.nlm.nih.gov/pubmed/27389476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29430
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