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Transgenic Eimeria tenella as a vaccine vehicle: expressing TgSAG1 elicits protective immunity against Toxoplasma gondii infections in chickens and mice

The surface antigen 1 of Toxoplasma gondii (TgSAG1) is a major immunodominant antigen and is widely considered an ideal candidate for the development of an effective recombinant vaccine against toxoplasmosis. Eimeria tenella, an affinis apicomplexan parasite with T. gondii, is a potential vaccine ve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tang, Xinming, Yin, Guangwen, Qin, Mei, Tao, Geru, Suo, Jingxia, Liu, Xianyong, Suo, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937369/
https://ncbi.nlm.nih.gov/pubmed/27387302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29379
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