Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia

Dematin is a relatively low abundance actin binding and bundling protein associated with the spectrin–actin junctions of mature erythrocytes. Primary structure of dematin includes a loosely folded core domain and a compact headpiece domain that was originally identified in villin. Dematin’s actin bi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lu, Yunzhe, Hanada, Toshihiko, Fujiwara, Yuko, Nwankwo, Jennifer O., Wieschhaus, Adam J., Hartwig, John, Huang, Sha, Han, Jongyoon, Chishti, Athar H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937361/
https://ncbi.nlm.nih.gov/pubmed/27073223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-692251
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