Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma

To interrogate signaling pathways activated in mantle cell lymphoma (MCL) in vivo, we contrasted gene expression profiles of 55 tumor samples isolated from blood and lymph nodes from 43 previously untreated patients with active disease. In addition to lymph nodes, MCL often involves blood, bone marr...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Saba, Nakhle S., Liu, Delong, Herman, Sarah E. M., Underbayev, Chingiz, Tian, Xin, Behrend, David, Weniger, Marc A., Skarzynski, Martin, Gyamfi, Jennifer, Fontan, Lorena, Melnick, Ari, Grant, Cliona, Roschewski, Mark, Navarro, Alba, Beà, Sílvia, Pittaluga, Stefania, Dunleavy, Kieron, Wilson, Wyndham H., Wiestner, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937360/
https://ncbi.nlm.nih.gov/pubmed/27127301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-681460
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