Vascular Regeneration in Ischemic Hindlimb by Adeno‐Associated Virus Expressing Conditionally Silenced Vascular Endothelial Growth Factor

BACKGROUND: Critical limb ischemia (CLI) is the extreme manifestation of peripheral artery disease, a major unmet clinical need for which lower limb amputation is the only option for many patients. After 2 decades in development, therapeutic angiogenesis has been tested clinically via intramuscular...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Boden, Jeffrey, Lassance‐Soares, Roberta Marques, Wang, Huilan, Wei, Yuntao, Spiga, Maria‐Grazia, Adi, Jennipher, Layman, Hans, Yu, Hong, Vazquez‐Padron, Roberto I., Andreopoulos, Fotios, Webster, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937238/
https://ncbi.nlm.nih.gov/pubmed/27231018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.001815
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