Chronic type 2 diabetes reduces the integrity of the blood-brain barrier by reducing tight junction proteins in the hippocampus

In the present study, we investigated the effects of type 2 diabetes-induced hyperglycemia on the integrity of the blood–brain barrier and tight junction markers in the rat hippocampus. Forty-week-old diabetic (Zucker diabetic fatty, ZDF) rats and littermate control (Zucker lean control, ZLC) rats w...

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Dettagli Bibliografici
Pubblicato in:J Vet Med Sci
Autori principali: YOO, Dae Young, YIM, Hee Sun, JUNG, Hyo Young, NAM, Sung Min, KIM, Jong Whi, CHOI, Jung Hoon, SEONG, Je Kyung, YOON, Yeo Sung, KIM, Dae Won, HWANG, In Koo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Society of Veterinary Science 2016
Soggetti:
Anatomy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937155/
https://ncbi.nlm.nih.gov/pubmed/26876499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.15-0589
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