Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis–Specific CD4(+) T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation

Helminth-infected individuals possess a higher risk of developing tuberculosis, but the precise immunologic mechanism of Mycobacterium tuberculosis control remains unclear. We hypothesized that a perturbation of the M. tuberculosis–specific CD4(+) T-cell response weakens the ability of macrophages t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: DiNardo, Andrew R., Mace, Emily M., Lesteberg, Kelsey, Cirillo, Jeffrey D., Mandalakas, Anna M., Graviss, Edward A., Orange, Jordan S., Makedonas, George
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936644/
https://ncbi.nlm.nih.gov/pubmed/27389351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw156
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados